College of Physicians and Surgeons
We have recently concluded a field study of the efficacy of bright-light administration in facilitating circadian rhythm adaptation to a new time zone after westward transmeridian travel. Circadian phase adapatation accelerated with evening light upon arrival in New York City from Zurich (Boulos Z et al. Aviation Space Environ Med 2002;73:953-963). Our Swiss colleagues recruited and screened volunteers and oversaw collection of preflight melatonin samples. Postflight treatment and testing were conducted in the GCRC. Under NIH support, the trial is being extended to bidirectional travel NYC/Zurich/NYC.
Project Leader/Principal Investigator
Department of Psychiatry
National Institute of Health (NIH)
Ziad Boulos, Ph.D., M. Mila Macchi, Ph.D.
Robert Steffen, MD University of Zurich Travel Clinic
World Health Organization