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United Kingdom (21)

Department/Center
Department of Genetics and Development
Leader
Stern, Claudio

Project
Molecular Mechanisms of Neural Induction
College of Physicians and Surgeons

A research program devoted to understanding the mechanisms of how the nervous system is established at the cellular and molecular level, using several model systems (Xenopus, chick, mouse) and . . .
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Department/Center
Department of Medicine
Leader
Bank, Arthur

Project
Clinical Gene Therapy Trial for Patients with Lymphoma at University College London, UK
College of Physicians and Surgeons

We are providing the MDR-containing retroviral supernatants for the CD34+ cell transduction trial in patients with lymphoma. We are continuing experimentation in improving the efficiency of . . .
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Department/Center
Department of Medicine
Leader
Bank, Arthur

Project
Gene Therapy in Cancer
College of Physicians and Surgeons

Using the multiple-drug resistance gene to provide hematopoietic stem cells with resistance to chemiotherpeutic agents. Using retroviral gene-transfer technique developed at Columbia. Patients with . . .
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Department/Center
Department of Medicine
Leader
Leibel, Rudolph

Project
Molecular Genetics of Obesity and Type 2 Diabetes: United Kingdom
College of Physicians and Surgeons

Current research activities include efforts to identify genes (and relevant allelic variants) related to obesity and/or type 2 diabetes in mice and humans. The lab has particular interest in the . . .
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Department/Center
Department of Neurology
Leader
Patterson, Marc

Project
A Phase I / II Randomised Controlled Study of OGT 918 in Niemann-Pick type C
College of Physicians and Surgeons

Niemann-Pick disease, type C (NPC), is a progressive neurodegenerative disorder in which abnormal intracellular lipid trafficking leads to accumulation of multiple lipids, including . . .
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Department/Center
Department of Neurology
Leader
Sacco, Ralph

Project
Glycine Antagonist in Neuroprotection: United Kingdom
College of Physicians and Surgeons

International advisory Board to plan and monitor 2 phase 3 clinical trials of acute stroke; UK, Australia, Germany, France, Finland. . . .
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Department/Center
Department of Neurology
Leader
Lewis, Linda

Project
Medical-Student Exchange Program: United Kingdom (1)
College of Physicians and Surgeons

Exchanges of medical students (fourth year) at http://www.mds.gmw.ac.uk/. . . .
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Department/Center
Department of Neurology
Leader
Lewis, Linda

Project
Medical-Student Exchange Program: United Kingdom (2)
College of Physicians and Surgeons

Four to eight week clinical electives available for senior students at the Edinburgh University Faculty of Medicine in Scotland. Research electives also available.(http://www.ed.ac.uk) . . .
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Department/Center
Department of Obstetrics and Gynecology
Leader
Birken, Steve

Project
Preparation of Reference Standards for Human Chorionic Gonadotropin
College of Physicians and Surgeons

Preparation of new international references standards for the pregnancy hormone human chorionic gonadotropin and its metabolites isolated from urine of pregnant women. To be distributed under WHO . . .
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Department/Center
Department of Pediatrics
Leader
Truman, John

Project
Oxford Workshop for the History of Childhood
College of Physicians and Surgeons

The Oxford Workshop for the History of Childhood at Magdalen College, Oxford, and the Program for Pediatrics and the Humanities at the College of Physicians and Surgeons of Columbia University are . . .
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Department/Center
Department of Pediatrics
Leader
Cairo, Mitchell

Project
Treatment of B-Cell Lymphoma in Children: United Kingdom
College of Physicians and Surgeons

Randomized multigroup, multicenter trial of chemotherapy in children with newly diagnosed B-Cell Lymphoma. Mitchel S. Cairo, MD, Study Chair. . . .
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Department/Center
Department of Pharmacology
Leader
Wit, Andrew

Project
Remodeling of Gap Junction in Reentrant Circuits
College of Physicians and Surgeons

Immunolocalization of cerinexin 43 gap junction protein in arrhythmogenic regions of canine model of myocardial infarction. . . .
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Department/Center
Department of Pharmacology
Leader
Franke, Thomas

Project
Role of PI3K/Akt Signaling Transduction in Higher Brain Function
College of Physicians and Surgeons

The PI3K/Akt kinase cascade in eukaryotic cells constitutes a pivotal signaling pathway involved in cell proliferation, cell survival, and metabolic cell responses. Recent studies have demonstrated . . .
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Department/Center
Department of Psychiatry
Leader
Toner, John

Project
Cross-National Comparison of Mental Hospital Closures in New York and London
College of Physicians and Surgeons

This project is a cross-national comparison of the effects on quality-of-life patient outcomes related to the closure of psychiatric hospitals in New York and London. The project takes a close look . . .
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Department/Center
Department of Psychiatry
Leader
Toner, John

Project
Geriatric Psychiatry Specialty Training
College of Physicians and Surgeons

The Columbia University Geriatric Psychiatry Residency and Fellowship Programs at the Stroud Center within the Faculty of Medicine is collaborating with the British Royal College of Psychiatrists to . . .
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Department/Center
Department of Psychiatry
Leader
Terwilliger, Joseph

Project
Wellcome Trust Summer Schools
College of Physicians and Surgeons

Teaching of statistical-genetics methods and genetic-epidemiology methods as part of the Wellcome Trust summer schools course on genetic analysis of complex traits. . . .
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Department/Center
Department of Radiation Oncology
Leader
Hall, Eric

Project
Hypersensitivity of Mammalian Cells to X-Rays at Low Doses of Radiation
College of Physicians and Surgeons

Earlier results indicated that the hypersensitivity of cells is greater at low doses (below 1Gy) of x-rays than at higher doses, due to the induction of repair processes at bigger doses. Of practical . . .
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Department/Center
Department of Radiology
Leader
Brown, Truman

Project
Predicting Tumor Response by 31-P Spectroscopy
College of Physicians and Surgeons

This multi-institutional project will examine localized 31-P MR spectra from the tumors of patients prior to their undergoing treatment for non-Hodgkin's Lymphoma (NHL). The spectra are quantitated . . .
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Department/Center
Department of Rehabilitation Medicine
Leader
Kronenberg, Fredi

Project
Rosenthal Center for Complementary & Alternative Medicine / The Prince of Wales's Foundation for Integrated Health Initiative
College of Physicians and Surgeons

This new collaboration involves educational and research components. We will take to England, the very successful Rosenthal Center CME courses on "Integrated Pain Medicine," "Botanical Medicine in . . .
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Department/Center
Department of Sociomedical Sciences
Leader
Nathanson, Constance

Project
Disease Prevention as Social Change: Society, Politics and Public Health in the U.S., Canada, Great Britain and France
Mailman School of Public Health

Comparative analysis of the sociology and politics of public health in the United States, Canada, Britain, and France through detailed examination of four policy arenas, tuberculosis and infant . . .
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Department/Center
Department of Sociomedical Sciences
Leader
Parker, Richard

Project
The International Working Group on Sexuality and Social Policy
Mailman School of Public Health

The International Working Group on Sexuality and Social Policy (IWGSSP) was constituted as a global forum composed of researchers and activists from a wide range of countries and regions of the . . .
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